Growth factors in the pathogenesis of radiation effects in normal tissues
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Growth factors in the pathogenesis of radiation effects in normal tissues

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Published by Urban & Vogel in München .
Written in English


  • Tissues -- Effect of radiation on -- Congresses.,
  • Radiation -- Physiological effect -- Congresses.

Book details:

Edition Notes

StatementWolfgang Dörr, editor.
SeriesMünchener medizinische Taschenbücher
ContributionsDörr, Wolfgang, Prof. Dr.
LC ClassificationsQP82.2.R3 G76 2001
The Physical Object
Pagination77 p. :
Number of Pages77
ID Numbers
Open LibraryOL19817233M
ISBN 103860941739

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Author(s): Dörr,Wolfgang,Prof. Dr. Title(s): Growth factors in the pathogenesis of radiation effects in normal tissues/ Wolfgang Dörr (editor). Country of Publication: Germany Publisher: München: . Effects of radiation exposure are observed in virtually all normal tissues. Early reactions occur primarily in turnover tissues (e.g., bone marrow, epidermis, mucosae of the gastrointestinal tract Author: Wolfgang Doerr. Pathogenesis of normal tissue side effects. Pathogenesis of late radiation effects. Chronic radiation effects are based on complex pathophysiological processes. and growth factors. This Author: Wolfgang Doerr. Radiation interference with gene expression. Quantitative and qualitative changes of the expression of genes after RT (25, 26) lead to the overproduction of a large number of cytokines and growth factors by irradiated cells that act in an autocrine and paracrine fashion and give birth to the finally recognizable histopathologic changes and clinical by:

  Growth Factors Radiation causes injury of normal tissue through cell killing, But in addition to mitotic and apoptotic cell death, radiation can induce changes in cellular function secondary to tissue injury Altered cell-to-cell communication Inflammatory responses Compensatory tissue hypertrophy of remaining normal tissue, and Tissue repair. THE EFFECTS OF SOLAR RADIATION ON PLANT GROWTH Joslyn Agard Selfridge High School and SKILL/NASA Honors Program South Dakota School of Mines & Technology ABSTRACT Phase 1 GrouDs and 3 This phase of this continuing project was completed in April, ,File Size: KB. Pathogenesis of Radiation-induced Normal Tissue Injury Vascular hypothesis: Rubin and Casarett () States that late radiation effects are caused by damage to blood vessels. This vascular injury, with a long latency reflecting the slow turnover time of the vasculature, leads to vessel occlusion, ischemia, and secondary loss of parenchymal cells. Rad Bio Test 1. STUDY. PLAY. The greater the proliferation and growth rate for tissues, the greater the radiosensitivity. It was discovered when researchers learned the effects of radiation exposure leading to the need to measure the levels of radiation causing specific effects.

The growth factors decreased the cellular doubling time in standard medium, but to a smaller extent than seen in growth factor defined medium. The radiation sensitivity and plating efficiency were slightly affected by growth factor defined versus standard growth conditions. Additional growth factor exposure was able to some extent to change the Cited by: 5. radiation. In tissues in which cells divide rarely, radiation damage to cells may remain Radiation effects on skeletal muscle Mihaela Jurdana1, 2 1College of Health Care Izola, Growth factors are highly specific pro-teins, which include hormones and cy-tokines that are involved in muscle hyper-File Size: KB. INTRODUCTION. Radiation dermatitis is one of the most common side effects of radiotherapy for cancer, affecting approximately 95 percent of patients receiving radiotherapy [].Cutaneous adverse effects of radiation therapy can be divided into early/acute reactions, occurring within 90 days of initiating treatment, and late effects, which often become apparent months to years after radiation.   Late effects of Radiotherapy on Normal Tissues 1. Radiation therapy is an integral part of cancer treatment 70% of all cancer-patients need radiation therapy at some point of the time With advances in treatment modalities, number of long-term cancer survivors has significantly Increased and they are at increased risk of developing radiation induced late toxicities.